Alcohols Effects on the Cardiovascular System
Gemfibrozil (Lopid) is a drug prescribed for certain types of high cholesterol or heart disease. After you take a dose of Lipitor, your body uses a certain enzyme (protein) to break down the drug. An increased level of the drug can make side effects from Lipitor more likely to occur. Heavy drinking is also linked with high levels of LDL cholesterol and triglycerides, which can further worsen heart health.
They can determine if they may be safe to take during your Lipitor treatment. They could occur with foods, supplements, vaccines, or even lab tests. Note that the information below does not include all other possible interactions with Lipitor.
Can I drink alcohol with Nexlizet or Nexletol?
If you need help reading or understanding this information, ask your doctor or pharmacist. It’s also important to read the label of Lipitor and other paperwork that comes with the drug. And the paperwork, sometimes called the prescribing information, may contain details about interactions. Your doctor or pharmacist can tell you more about taking metformin with Lipitor. For more information about taking Zetia with Lipitor, talk with your doctor or pharmacist.
Impact of Drinking Patterns and Types of Alcoholic Beverages on Risk
If you’re worried about any other side effects speak to your doctor. People are often told to take their statin at night, because some statins work better when taken at this time. If you make it part of a routine, you’re more likely to remember it. You could take it when getting ready for bed, before or after brushing your teeth.
- Several reports indicate that alcohol first exerts a seemingly positive effect, followed by a more negative impact (i.e., it is biphasic) on the endothelial–nitric oxide–generating system.
- This suggests a direct or indirect role for ethanol-mediated oxidative stress in the heart (Jiang et al. 2012; Tan et al. 2012).
- Before you take Lipitor, be sure to talk with your doctor about your health history.
- However, these changes were transient, with small changes from baseline.
Whether you’re taking statins or considering whether to take them, you may have questions about this cholesterol-lowering medication. Much of the alcohol that flows into your system after tipping back a glass finds its way to your liver for a digestive after-party. Alcohol is broken down in your liver and reconstructed as cholesterol and triglycerides. HDL protects heart health because it collects excess cholesterol and transports it to your liver, where it can be removed or recycled. If you’re taking statins and need to take one of these medicines, a doctor may prescribe an alternative statin or your current statin at a lower dosage. In some cases, they may recommend that you temporarily stop taking your statin.
Preventing interactions
Statins should not be taken if you have liver disease or if blood tests suggest that your liver may not be working properly. After you take a dose of Lipitor, your body uses certain enzymes to break down the drug. St. John’s Wort causes your body to increase the activity of these enzymes. This may reduce the level of Lipitor in your body, causing the drug to work less well than usual.
Data from transgenic animal models and pharmacologic approaches strongly support a role for ethanol-induced oxidative stress in CV disease. In addition, there was no evidence of nitrative damage in mice bred to disrupt (i.e., knock out) the gene for angiotensin I receptor (AT1-KO) that had been given ethanol for a similar length of time (Tan et al. 2012). Both experimental approaches also prevented accumulation of ethanol-induced scarring (collagen and fibronectin); apoptotic cell death; and changes in the size, shape, and function of the heart after injury to heart muscle (ventricular remodeling). It has been debated whether beverage type has differential effects. Some investigators have suggested that drinking wine may offer more protection against CV disease because it contains polyphenols, such as resveratrol and flavonoids, which are micronutrients with antioxidant activity (Tangney and Rasmussen 2013). However, among studies designed to examine the influence of beverage type, no differences have been found in CV disease outcomes or biologic markers, such as HDL-c (Mukamal et al. 2003a; Volcik et al. 2008).
Type of Alcoholic Beverage Consumed
Taking them together may raise your risk of side effects from Lipitor, including muscle problems such as myopathy and rhabdomyolysis. Your doctor can determine whether it’s safe for you to take diltiazem and Lipitor together. If your doctor prescribes both drugs, they’ll likely monitor you closely for side effects, especially muscle-related side effects, such as muscle pain. After you take a dose of Lipitor, your body uses a certain enzyme to break down the drug. Lipitor (atorvastatin) is a brand-name oral tablet that’s prescribed to treat high cholesterol and lower the risk of cardiovascular problems.
Cardiovascular disease is a life-long, low-grade chronic inflammatory and oxidative disease, initiated by elevated low density lipoprotein (LDL) cholesterol levels and deposition in the intima forming atheromatous plaque. This plaque may eventually rupture, triggering thrombus formation which may occlude the blood vessel leading to a MACE can you snort zolpidem 72. In this setting, reduced concentrations of intermediate biomarkers of inflammation, oxidation, and coagulation as well as improving the lipid profile may decrease the risk of an eventual MACE.